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Dexamethasone and 1,25(OH)2vitamin D3modulate the synthesis of insulin-like growth factor-I in osteoblast-like cells

✍ Scribed by Theresa L. Chen; Joanne Bednarz Mallory; Raymond L. Hintz


Book ID
110554801
Publisher
Springer
Year
1991
Tongue
English
Weight
755 KB
Volume
48
Category
Article
ISSN
1432-0827

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We investigated the existence of a capacitative Ca2+ entry (CCE) pathway in ROS 17/2.8 osteoblast-like cells and its responsiveness to 1,25-dihydroxy-vitamin D3 [1,25(OH)2D3]. Depletion of inner Ca2+ stores with thapsigargin or 1,25(OH)2D3 in the absence of extracellular Ca2+ transiently elevated cy