Insulin-like growth factor-I stimulates45Ca-accumulation in cultures of osteoblast-like cells
โ Scribed by Osamu Kozawa; Kensuke Takatsuki; Haruhiko Tokuda; Masaichi Miwa; Katsuhiro Kotake; Masahiro Yoneda; Yutaka Oiso; Hidehiko Saito
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 316 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0914-8779
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Insulin-like growth factor (IGF) I is an autocrine regulator of bone remodeling which inhibits bone collagen degradation and interstitial collagenase 3 mRNA levels. The mechanism of this inhibitory effect on collagenase 3 expression is not known. We tested the effects of IGF I on collagenase 3 gene
Insulin-like growth factor I (IGF-I) and high concentrations of insulin have been shown to stimulate an increase in the number of oligodendrocytes that appear in developing monolayer cultures of rat brain cells (McMorris et al.,