✦ LIBER ✦

Insulin-like growth factor I stimulates oligodendrocyte development and myelination in rat brain aggregate cultures

✍ Scribed by Dr. R. L. Mozell; Dr. F. A. McMorris

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 957 KB
Volume: 30
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490300214

No coin nor oath required. For personal study only.

✦ Synopsis

Insulin-like growth factor I (IGF-I) and high concentrations of insulin have been shown to stimulate an increase in the number of oligodendrocytes that appear in developing monolayer cultures of rat brain cells (McMorris et al.,

📜 SIMILAR VOLUMES

In vivo actions of fibroblast growth fac

In vivo actions of fibroblast growth factor-2 and insulin-like growth factor-I on oligodendrocyte development and myelination in the central nervous system

✍ Diane R. Goddard; Martin Berry; Arthur M. Butt 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 729 KB

The in vivo effects of fibroblast growth factor-2 (FGF-2) and insulin-like growth factor-I (IGF-I) on oligodendrocytes and CNS myelination were determined in the postnatal rat anterior medullary velum (AMV) following injection of both cytokines into the cerebrospinal fluid. Either FGF-2, IGF-I, or s

Expression of insulin-like growth factor

Expression of insulin-like growth factor II and receptors for insulin-like growth factor II, insulin-like growth factor I and insulin in isolated and cultured rat hepatocytes

✍ Eugenia Lamas; Frédérique Zindy; Danielle Seurin; Christiane Guguen-Guillouzo; C 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 714 KB

Insulin-like growth factor I1 is believed to play an important role in fetal growth and development. The insulin-like growth factor I1 gene expression is tissue specific and developmentally regulated. We have previously shown an enhanced level of insulin-like growth factor I1 messenger RNA and prote

Expression of insulin-like growth factor

Expression of insulin-like growth factor-binding protein messenger RNAs in developing rat oligodendrocytes and astrocytes

✍ Reema Mewar; F. Arthur McMorris 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 2 views

Insulin-like growth factors, IGF-I and IGF-II, are potent regulators of oligodendrocyte development. Most of the IGF present in vivo is bound to members of a family of six high-affinity IGF-binding proteins (IGFBPs), which can either potentiate or inhibit IGF action, depending on other conditions. A

Insulin-like growth factor-I (IGF-i) sti

Insulin-like growth factor-I (IGF-i) stimulates protein synthesis and collagen gene expression in monolayer and lattice cultures of fibroblasts

✍ Philippe Gillery; Armelle Leperre; François-Xavier Maquart; Jacques-Paul Borel 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 800 KB

## Abstract Fibroblasts cultivated in three‐dimensional tissue‐like matrices are characterized by a slowed metabolism and a decrease of protein synthesis, unless they are submitted to physical tensions. We checked the effects of insulin like growth factor‐I (IGF‐I), known as a potent stimulator of

Insulin-like growth factor-I (IGF-I) pro

Insulin-like growth factor-I (IGF-I) protects myelination from undernutritional insult: Studies of transgenic mice overexpressing IGF-I in brain

✍ Ping Ye; Kee-Hyoung Lee; A. Joseph D'Ercole 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 258 KB

Using insulin-like growth factor-I (IGF-I)-overexpressing transgenic (Tg) mice as a model, we have shown that IGF-I promotes myelination by increasing the number of oligodendrocytes and stimulating the expression of myelin-specific protein genes. In the present study, we investigated whether IGF-I p

Low-intensity laser irradiation stimulat

Low-intensity laser irradiation stimulates bone nodule formation via insulin-like growth factor-I expression in rat calvarial cells

✍ Noriyoshi Shimizu; Kotoe Mayahara; Takeshi Kiyosaki; Akikuni Yamaguchi; Yasuhiro 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 1 views

## Abstract ## Background and Objective We previously reported that low‐intensity laser irradiation stimulated bone nodule formation through enhanced cellular proliferation and differentiation. However, the mechanisms of irradiation are unclear. Thus, we attempted to determine the responsibility o