𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Bloom's syndrome

✍ Scribed by David Bloom; James German


Publisher
Springer
Year
1972
Tongue
English
Weight
48 KB
Volume
16
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Bloom's syndrome
✍ A. Spanos; R. Holliday; J. German πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 752 KB

The biochemical defect in Bloom's syndrome (BS) remains unknown, but two characteristic features of BS cells point to a disturbance of DNA replication, namely, an excessive number of sister-chromatid exchanges (SCEs) in bromodeoxyuridine (BrdU)-substituted cells and an abnormally slow rate of replic

Cancer predisposition in bloom's syndrom
✍ Neil F. Sullivan; Anne E. Willis πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 531 KB

This article focusses upon defining those factors which may contributc to the pathogenesis of cancer. The molecular basis of tumour etiology is discussed with reference to cancer predisposing syndromes, and in particular to the human inherited disease, Bloom's syndrome. In Bloom's syndrome, patients

Sensitivity of Bloom's syndrome lymphocy
✍ Alena B. Krepinsky; J. A. Heddle; J. German πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 357 KB

Ethyl methanesulfonate induced several times as many sister. chromatid exchanges (SCEs) in lymphocytes from individuals affected with Bloom's syndrome as in lymphocytes from controls or heterozygotes. In cultures of cells from an individual with Bloom's syndrome who had two populations of lymphocyte

Cytogenetic investigations in a new case
✍ K. Sperling; U. Goll; J. Kunze; E. -K. LΓΌdtke; M. Tolksdorf; G. Obe πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 353 KB

Cytogenetic studies of an 8-year-old caucasian girl with typical but mild manifestation of Bloom's syndrome showed a characteristic increase of homologous chromatid translocations and prematurely condensed chromosomes. The average frequency of sister chromatid exchanges (SCE) in lymphocytes with 133