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Blood glutathione as a surrogate marker of cancer tissue glutathione S-transferase activity in non-small cell lung cancer and squamous cell carcinoma of the head and neck

✍ Scribed by E Ferruzzi; R Franceschini; G Cazzolato; C Geroni; C Fowst; U Pastorino; N Tradati; J Tursi; R Dittadi; M Gion


Book ID
117660004
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
245 KB
Volume
39
Category
Article
ISSN
0959-8049

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Differences in genetic susceptibility to tobacco-induced carcinogenesis appear to modulate an individual's risk of squamous-cell carcinoma of the head and neck (SCCHN). Risk for SCCHN may be associated with the null alleles of the carcinogen-metabolizing genes glutathione-S-transferase (GST) T1 and