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Bisprolinediamides with the Binaphthyl Backbone as Organocatalysts for the Direct Asymmetric Aldol Reaction.

โœ Scribed by Dorota Gryko; Bartlomiej Kowalczyk; Lukasz Zawadzki


Publisher
John Wiley and Sons
Year
2006
Weight
24 KB
Volume
37
Category
Article
ISSN
0931-7597

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L-Prolinethioamides โ€“ Efficient Organoca
โœ Dorota Gryko; Radosล‚aw Lipiล„ski ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 81 KB ๐Ÿ‘ 2 views

## Abstract A series of novel Lโ€proline derived thioamides has been synthesised. They have been evaluated as organocatalysts in the direct asymmetric aldol reaction for the first time. Thioamides exhibit catalytic ability higher than proline itself and the model aldol reaction of 4โ€cyanobenzaldehyd