Bis(N,N-dimethylcarbamoyloxymethyl) 2', 3'-dideoxyuridine 5'-monophosphate (DlvlrddUMP) (la) was synthesized as a potential membrane-permeable prodrug of ddUMP (3). Unlike the bis(pivaloyloxymethyl) analog, I b, la was completely resistant to degradation by plasma enzymes -a property that should enh
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Bis(carbamoyloxymethyl) Esters of 2′,3′-Dideoxyuridine 5′-monophosphate (ddUMP) as Potential ddUMP Prodrugs
✍ Scribed by Saeed R. Khan; Srinivas K. Kumar; David Farquhar
- Publisher
- Springer US
- Year
- 2005
- Tongue
- English
- Weight
- 393 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0724-8741
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