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Bisabolane-Type Sesquiterpenoids from the Rhizomes of Glochidion coccineum

✍ Scribed by Hai-Tao Xiao; Xiao-Yan Hao; Xian-Wen Yang; Yue-Hu Wang; Yang Lu; Ying Zhang; Suo Gao; Hong-Ping He; Xiao-Jiang Hao


Publisher
John Wiley and Sons
Year
2007
Tongue
German
Weight
93 KB
Volume
90
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A novel bisabolane‐type sesquiterpenoid lactone, glochicoccin A (1), and three new norbisabolane sesquiterpenoids, glochicoccins B–D (24), together with two known norbisabolane sesquiterpenoids, phyllaemblic acid (5) and phyllaemblic acid methyl ester (6), were isolated from the rhizomes of Glochidion coccineum. Their structures were elucidated by different spectroscopic (IR, UV, NMR) and mass‐spectrometric (MS) techniques. The structure and relative configuration of 1 was confirmed by single‐crystal X‐ray diffraction (Fig. 2). None of the compounds were found to exhibit cytotoxic or antioxidant activities.


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