New Dammarane-Type Saponins from the Rhizomes of Panax japonicus

✍ Scribed by Min Zhou; Min Xu; Dong Wang; Hong-Tao Zhu; Chong-Ren Yang; Ying-Jun Zhang

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: German
• Weight: 236 KB
• Volume: 94
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.201100085

✦ Synopsis

Abstract

Phytochemical investigation of the rhizomes of Panax japonicus C. A. Meyer (Araliaceae) resulted in the isolation of two new dammarane‐type triterpenoid saponins, yesanchinoside R~1~ (1) and yesanchinoside R~2~ (2), together with one new natural product, 6′′′‐O‐acetylginsenoside Re (3). In addition, 25 known compounds, including 23 triterpenoid saponins, 4–26, β‐sitosterol 3‐O‐β‐D‐glucopyranoside (27), and ecdysterone (28), were also identified. The known saponins 12, 15, and 18–22 were reported for the first time from the title plant. Their structures were elucidated on the basis of detailed spectroscopic analyses, including 1D‐ and 2D‐NMR techniques, as well as acidic hydrolysis.