Biphenotypic expression in a case of acute leukemia with pericentric inv(6)(p12q24)
β Scribed by Lily Kerketta; V. Babu Rao; Manisha Madkaiker; Kanjaksha Ghosh; Dipika Mohanty; Farah Jijina
- Book ID
- 113512615
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 201 KB
- Volume
- 159
- Category
- Article
- ISSN
- 0165-4608
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We report on a novel chromosomal aberration, inv(8)(p11q24), in an M5 acute myeloid leukemia. We show by fluorescence in situ hybridization and Southern blot analyses that a t(8;16)(p11;p13) is masked by this inversion. The translocation targets the MOZ gene from the 8p11 and the CBP gene from the 1