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Biotransformation and excretion of nitromethaqualone in rats and humans

โœ Scribed by M. Van Boven; P. Daenens


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
750 KB
Volume
71
Category
Article
ISSN
0022-3549

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In vivo biotransformation and biliary ex
โœ B. I. Ghanayem; A. E. Ahmed ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 536 KB

1-14C-Acrylonitrile (VCN) was given orally to rats, 27% of the given dose was excreted in bile in 6 h. When 1-14C-VCN was given to overnight fasted or cobaltous chloride treated rats, a significant increase in the biliary excretion occurred. Pretreatment of rats with phenobarbital produced no change