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Biosynthesis of o-succinylbenzoic acid II: Properties of o-succinylbenzoic acid synthase, an enzyme involved in vitamin K2 biosynthesis

โœ Scribed by Alfons Weische; Waltraut Garvert; Eckhard Leistner


Book ID
115707465
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
760 KB
Volume
256
Category
Article
ISSN
0003-9861

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Vitamin K (menaquinone) biosynthesis in
โœ Janet L. Popp; Christine Berliner; Ronald Bentley ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 640 KB

An early enzyme in menaquinone (vitamin K2) biosynthesis is the synthase forming 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) from isochorismic acid. In turn, SHCHC is aromatized to o-succinylbenzoic acid (OSB) by OSB synthase. An assay for the combined activity of these two enz