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Biosynthesis of iodinin: Incorporation of [6-14C]shikimic acid

✍ Scribed by R.B. Herbert; F.G. Holliman; P.N. Ibberson


Publisher
Elsevier Science
Year
1974
Tongue
French
Weight
185 KB
Volume
15
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Incorporation of shikimic acid into iodi
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The role of shikimic acid (1) as precursor for a number of antibiotic phenazines' has been established among others for iodinin (2). Our previous results" have led to the conclusion that for iodinin the possible pairing schemes of two shikimic acid molecules can be narrowed down to schemes A and B.

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## Abstract Shikimic‐6‐^13^C acid, 43 Β± 5% enriched, was synthesized from 91% enriched acetic‐2‐^13^C acid via 91% enriched phosphoenolpyruvic‐3‐^13^c acid. The latter intermediate was condensed with erythrose‐4‐phosphate by a cell free extract of __E__. __coli__ 83‐24.

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