Biosynthesis of deuterated benzylpenicillins II: Isolation and characterization of a highly deuterated benzylpenicillin
β Scribed by Bruce C. Carlstedt; Henry L. Crespi; Martin I. Blake; Joseph J. Katz
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 562 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0022-3549
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Fully deuterated griseofulvin was isolated in pure form from P. janczewskii grown in a completely deuterated medium. Direct fermentation and a replacement culture technique were used. The isolated antibiotic was purified by thin-layer chromatography and characterized by ultraviolet, infrared, and nu