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Biomonitoring of the cytogenetic effect of antitumor therapy by means of micronucleus assay in exfoliated epithelial cells

✍ Scribed by A. K. Nersesyan

Book ID
111495653
Publisher
Allerton Press Inc
Year
2007
Tongue
Ukrainian
Weight
105 KB
Volume
41
Category
Article
ISSN
0095-4527

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The exfoliated cell micronucleus (MN) assay using fluorescent in situ hybridization (FISH) with a centromeric probe is a rapid method for determining the mechanism of MN formation in epithelial tissues exposed to carcinogenic agents. Here, we describe the use of this assay to detect the presence or