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The in vitro micronucleus assay for detection of cytogenetic effects induced by mutagen-carcinogens: comparison with the in vitro sister-chromatid exchange assay

✍ Scribed by C. Lasne; Z.W. Gu; W. Venegas; I. Chouroulinkov

Book ID
113250789
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
796 KB
Volume
130
Category
Article
ISSN
0165-1161

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In vitro sister chromatid exchange (SCE) and chromosome aberration (ABS) tests have been extensively used to identify potential rodent carcinogens. A number of measures of potency were developed to describe in vitro SCE and ABS test results: the dose needed to induce a unit increase over the control