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Local genotoxic effects of formaldehyde in humans measured by the micronucleus test with exfoliated epithelial cells

✍ Scribed by Günter Speit; Oliver Schmid

Book ID
116760190
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
149 KB
Volume
613
Category
Article
ISSN
1383-5742

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The exfoliated cell micronucleus (MN) assay using fluorescent in situ hybridization (FISH) with a centromeric probe is a rapid method for determining the mechanism of MN formation in epithelial tissues exposed to carcinogenic agents. Here, we describe the use of this assay to detect the presence or