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Biologically Active Iridoids from Hedyotis diffusa

✍ Scribed by Bo Ding; Wei-Wei Ma; Yi Dai; Hao Gao; Yang Yu; Ye Tao; Yi Zhong; Xin-Sheng Yao

Publisher: John Wiley and Sons
Year: 2010
Tongue: German
Weight: 196 KB
Volume: 93
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.201000129

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✦ Synopsis

Two new iridoids, 10-O-benzoyl-6'-O-a-l-arabino(1 ! 6)-b-d-glucopyranosylgeniposidic acid (1), deacetyl-6-ethoxyasperulosidic acid methyl ester (2), along with 14 other known iridoids, were isolated from the whole plant of Hedyotis diffusa Willd. Their structures were determined on the basis of spectroscopic analysis. The short-term-memory-enhancement activities of compounds 1, 7 -9, 11, and 13 were evaluated on an Ab transgenic drosophila model.

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