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Biological functions of the ING family tumor suppressors

✍ Scribed by E. I. Campos; M. Y. Chin; W. H. Kuo; G. Li

Book ID: 105757908
Publisher: Springer
Year: 2004
Tongue: English
Weight: 268 KB
Volume: 61
Category: Article
ISSN: 1420-682X
DOI: 10.1007/s00018-004-4199-4

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## Abstract The Inhibitor of Growth 1 (ING1) gene has been identified and characterized as a Type‐II tumor suppressor gene (TSG). Subsequently, 4 additional members of the family were identified by homology search. ING proteins contain a nuclear localization sequence (NLS) and a plant homeo domain