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Biochemistry of 1,3-butadiene metabolism and its relevance to 1,3-butadiene-induced carcinogenicity

โœ Scribed by Adnan A. Elfarra; Renee J. Krause; Rebecca R. Selzer

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
633 KB
Volume
113
Category
Article
ISSN
0300-483X

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Renal, biliary, pulmonary and faecal excretion experiments were carried out with labelled hexachloro-1,3butadiene ([I4C]HCBD) in male Sprague-Dawley rats, given orally (p.0.) and intravenously (i.v.) in doses of 1 and 100 mg kg-' as a solution in polyethylene glycol. The radioactivity excreted over