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Biochemical, molecular and behavioral phenotypes of Rab3A mutations in the mouse

✍ Scribed by S. Yang; M. Farias; D. Kapfhamer; J. Tobias; G. Grant; T. Abel; M. Bućan

Book ID: 111273045
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 398 KB
Volume: 6
Category: Article
ISSN: 1601-1848
DOI: 10.1111/j.1601-183x.2006.00235.x

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Rab3A, a member of the small GTP-binding protein superfamily, has been implicated in regulated exocytosis at presynapses. At fertilization, sperm-egg fusion induces cytosolic calcium mobilization and cortical granule (CG) exocytosis in the egg. However, it is not yet clear whether Rab3A is involved