Biochemical and molecular analysis of spontaneous and induced mutations at the mouse Mod-1 locus
β Scribed by Ronald R. Cobb; James G. Burkhart; Jeffrey S. Dubins; Lois B. Barnett; Susan E. Lewis
- Book ID
- 113251925
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 663 KB
- Volume
- 234
- Category
- Article
- ISSN
- 0165-1161
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Communicated by Steve S. Sommer Hypoxanthine phosphoribosyl transferase (HPRT, also known as HGPRT) is an often-used genetic marker in eukaryotic cells. The gene is conserved from bacteria to human, with retained catalytic activity, although substrate specificity may have changed, and the enzym
A previously identified complex mutation, affecting exon 28 of the neurofibromatosis type 1 gene, was employed for the analysis of the expression pattern in primary cultures of neurofibroma cells and melanocytes from a cafΓ©-au-lait macule of the patient, respectively. Reverse transcription and subse