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Biochemical analysis of HLA class I subunits expression in breast cancer tissues

✍ Scribed by Maria Pia Pistillo; Guido Nicolò; Sandra Salvi; Paolo Capanni; Luisa Perdelli; Gennaro Pasciucco; Giovanni Battista Ferrara

Book ID
117416006
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
918 KB
Volume
61
Category
Article
ISSN
0198-8859

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✍ Ingibjörg Guđmundsdóttir; Jón Gunnlaugur Jónasson; Helgi Sigurđsson; Kristrún Ól 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 620 KB

Loss of surface expression of class I major histocompatibility antigens is commonly observed in malignant tumors and has been considered one of the mechanisms for escape from cytotoxic T cells. However, natural killer cells kill cells lacking HLA class I antigens. In the present study, we characteri