Altered expression of HLA class I antige
β
IngibjΓΆrg GuΔmundsdΓ³ttir; JΓ³n Gunnlaugur JΓ³nasson; Helgi SigurΔsson; KristrΓΊn Γl
π
Article
π
2000
π
John Wiley and Sons
π
French
β 620 KB
Loss of surface expression of class I major histocompatibility antigens is commonly observed in malignant tumors and has been considered one of the mechanisms for escape from cytotoxic T cells. However, natural killer cells kill cells lacking HLA class I antigens. In the present study, we characteri