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Bioavailability of microsphere-entrapped cyclosporine A in the cornea and aqueous of rabbits

โœ Scribed by C. Armitage Harper; Bahram Khoobehi; Gholam A. Peyman; Bryan M. Gebhardt; Weldon A. Dunlap

Publisher
Springer Netherlands
Year
1993
Tongue
English
Weight
464 KB
Volume
17
Category
Article
ISSN
0165-5701

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## Abstract Rabbit (dark irides and albino) and human corneas were excised and mounted in a Luciteยฎ chamber in order to determine the permeability of cyclophosphamideโ€^14^C and to identify its metabolites. The chromatographic scans obtained from the developed thinโ€layer plates showed only one peak