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Clearance of microsphere-entrapped 5-fluorouracil and cytosine arabinoside from the vitreous of primates

✍ Scribed by Gholam A. Peyman; Mandi Conway; Bahram Khoobehi; Kenneth Soike

Publisher
Springer Netherlands
Year
1992
Tongue
English
Weight
332 KB
Volume
16
Category
Article
ISSN
0165-5701

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The authors have developed a new method of drug delivery into the brain using implantable biodegradable microspheres. In this study, this method was used to provide localized and sustained delivery of 5-fluorouracil (5-FU) after the surgical resection of glioblastoma. This antimetabolite and radiose