Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice
✍ Scribed by Manach, C; Morand, C; Gil-Izquierdo, A; Bouteloup-Demange, C; Rémésy, C
- Book ID
- 110022289
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 199 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0954-3007
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract It has been reported that the intestinal absorption of celiprolol, an antihypertensive drug, is inhibited when it is taken with orange juice; it has been suggested that element(s) in citrus juice are responsible for this. In the present study, the pharmacokinetic interaction between cel
## Abstract Human urine was collected over a 24 h period after the consumption of 250 mL of (i) water, (ii) orange juice, and (iii) orange juice plus 150 mL of full fat natural yoghurt. The orange juice contained 168 μmol of hesperetin‐7‐__O__‐rutinoside and 18 μmol of naringenin‐7‐__O__‐rutinoside
Previous studies with rats indicate that nifedipine undergoes both hepatic and extrahepatic presystemic metabolism after peroral (po) administration, and that its bioavailability is increased and absorption delayed by concomitant administration of grapefruit juice concentrate (GJC). Hence, the effec