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Bioanalytical LC-MS/MS method validation for plasma determination of topiramate in healthy Indian volunteers

โœ Scribed by Dipanjan Goswami; Ajay Kumar; Arshad H. Khuroo; Tausif Monif; Shamsur Rab


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
673 KB
Volume
23
Category
Article
ISSN
0269-3879

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Determination of plasma topiramate conce
โœ Jin-Hee Park; Yoo-Sin Park; Min-Ho Lee; Si-Youn Rhim; Jae-Chul Song; Soo-Jin Lee ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 345 KB ๐Ÿ‘ 2 views

## Abstract A rapid, simple and validated liquid chromatography coupled to tandem mass spectrometric method (LCโ€MS/MS) for topiramate analysis in human plasma has been applied to pharmacokinetic and bioequivalence studies in 24 healthy male Korean volunteers. The procedure involves a simple liquid