𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Rational design for variability minimization in bioanalytical method validation: illustration with LC-MS/MS assay method for terbinafine estimation in human plasma

✍ Scribed by Sanjay Gurule; Arshad Khuroo; Tausif Monif; Dipanjan Goswami; Arabinda Saha

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
577 KB
Volume
24
Category
Article
ISSN
0269-3879

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Validation of LC/MS Electrospray Ionisat
Validation of LC/MS Electrospray Ionisation Method for the Estimation of Ursodiol in Human Plasma and ITS Application in Bioequivalence STUDY
✍ Sonu Sundd Singh; Hiten Shah; Sapna Gupta; Manish Jain; Kuldeep Sharma; Harshvar πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 81 KB

## Abstract A novel High Performance Liquid Chromatography β€” electrospray mass spectrometric method has been developed for the estimation of Ursodiol (Ursodeoxycholic acid)‐a bile acid, in human plasma using Ornidazole as internal standard. The methodology involved solid phase extraction of the ana

Development and validation of a sensitiv
Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of pramipexole in human plasma: application to a clinical pharmacokinetic study
✍ D. Vijaya Bharathi; Kishore Kumar Hotha; P. V. Vidya Sagar; S. Sirish Kumar; A. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 396 KB πŸ‘ 2 views

## Abstract A highly sensitive and specific LC‐MS/MS method has been developed and validated for the estimation of pramipexole (PPX) with 500Β Β΅L human plasma using memantine as an internal standard (IS). The API‐4000 was operated under multiple‐reaction monitoring mode (MRM) using the electrospray

Development and validation of a high-sen
Development and validation of a high-sensitivity liquid chromatography/tandem mass spectrometry (LC/MS/MS) method with chemical derivatization for the determination of ethinyl estradiol in human plasma
✍ Wilson Z. Shou; Xiangyu Jiang; Weng Naidong πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 192 KB πŸ‘ 2 views

## Abstract An ultra‐sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the analysis of oral contraceptive ethinyl estradiol (EE) was developed and validated over the curve range of 2.5–500 pg/mL using 1 mL of human plasma sample. Ethinyl estradiol and the internal stand