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Sensitive LC-MS-MS method for the determination of tiopronin in human plasma

✍ Scribed by Bo Jiang; Yu Xu; Fang Xu; Junjie Sun; Na Li; Yanan Luo; Qingxiang Guo

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
713 KB
Volume
24
Category
Article
ISSN
0269-3879

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## Abstract The anticancer drug capecitabine and its metabolites [including the active metabolite 5‐fluorouracil (5‐FU)] display high pharmacokinetic inter‐patient variability. Such variability, which may lead to treatment failure or toxicity, could need drug concentration measurement to individual