Binol-Derived Monodentate Phosphites and Phosphoramidites with Phosphorus Stereogenic Centers: Novel Ligands for Transition-Metal Catalysis

✍ Scribed by Manfred T. Reetz; Jun-An Ma; Richard Goddard

• Book ID: 101531589
• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 154 KB
• Volume: 117
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/ange.200461624

✦ Synopsis

Recently three groups independently reported that binolderived monodentate phosphites 1 a, [1] phosphonites 1 b, [2] and phosphoramidites 1 c [3] are efficient ligands in rhodiumcatalyzed asymmetric olefin hydrogenation (ee values = 90-99 %; binol = 2,2'-dihydroxy-1,1'-binaphthyl). A preliminary