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BINOL-based azacrown ether catalyzed enantioselective Michael addition: asymmetric synthesis of α-aminophosphonates

✍ Scribed by Truong Son Pham; János B. Czirok; László Balázs; Krisztina Pál; Miklós Kubinyi; István Bitter; Zsuzsa Jászay


Book ID
108284660
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
422 KB
Volume
22
Category
Article
ISSN
0957-4166

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Enantioselective Michael addition of 2-n
✍ Tibor Bakó; Péter Bakó; György Keglevich; Nikoletta Báthori; Mátyás Czugler; Ján 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 401 KB

The chiral monoaza-15-crown-5 type lariat ethers 1 and 2 derived from a-D-glucose and from D-mannitol, respectively, have been applied as phase transfer catalysts in the enantioselective Michael addition of 2-nitropropane to aromatic 3b-c and heteroaromatic 3d-h chalcone analogues. Among the catalys