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Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α-dystroglycan and several extracellular matrix proteins

✍ Scribed by Talts, Jan F.; Andac, Zeynep; Göhring, Walter; Brancaccio, Andrea; Timpl, Rupert


Book ID
111746315
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
248 KB
Volume
18
Category
Article
ISSN
0261-4189

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Identification of a heparin binding site
✍ Ichiro Yoshida; Ken-Ichiro Tashiro; Akira Monji; Isao Nagata; Yoshihito Hayashi; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 342 KB

The carboxy-terminal globular domain (G-domain) of the laminin ␣1 chain has been shown to promote heparin binding, cell adhesion, and neurite outgrowth. In this study, we defined the potential sequences originating from the G-domain of laminin ␣1 chain which possess these functional activities. A se