Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified
✦ LIBER ✦
The N-terminal globular domain of the laminin α1 chain binds to α1β1 and α2β1 integrins and to the heparan sulfate-containing domains of perlecan
✍ Scribed by Norbert Ettner; Walter Göhring; Takako Sasaki; Karlheinz Mann; Rupert Timpl
- Book ID
- 117109268
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 493 KB
- Volume
- 430
- Category
- Article
- ISSN
- 0014-5793
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