Binding of metronidazole and its derivatives to plasma proteins: An assessment of drug binding phenomenon
โ Scribed by Dilip R. Sanvordeker; Yie W. Chien; Teng K. Lin; Howard J. Lambert
- Book ID
- 102915147
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 524 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3549
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๐ SIMILAR VOLUMES
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Although displacement from plasma protein binding (dPB) is usually of little clinical significance, it should be taken into account when interpreting changes in total plasma concentrations of drugs subject to metabolically based drug-drug interactions (mDDI). The aim of this study was to develop an
Data on the binding of imipramine, desipramine, and 3-chlorodesmethylimipramine to plasma proteins have been obtained over a wide range of ligand concentration using a modified equilibrium dialysis technique. Plasma proteins other than albumin do not appreciably contribute to complex formation with