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Binding of Actinomycin D to Single-Stranded DNA of Sequence Motifs d(TGTCTnG) and d(TGTnGTCT)

✍ Scribed by Chen, Fu-Ming; Sha, Feng; Chin, Ko-Hsin; Chou, Shan-Ho


Book ID
118515607
Publisher
Biophysical Society
Year
2003
Tongue
English
Weight
217 KB
Volume
84
Category
Article
ISSN
0006-3495

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Actinomycin D Binding to Unstructured, S
✍ Hoon Yoo; Randolph L. Rill πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 100 KB πŸ‘ 1 views

## Abstract Actinomycin D is an anticancer antibiotic best know for inhibiting transcription by binding double‐stranded DNA. Tight, sequence selective binding of actinomycin to single‐stranded DNA is also known, however, and is implicated in biological activities including inhibition of (βˆ’) strand