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The binding of actinomycin D and adriamycin to supercoiled DNA, single-stranded DNA and polynucleotides

✍ Scribed by H. Simpkins; L.F. Pearlman

Book ID
119119263
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
662 KB
Volume
783
Category
Article
ISSN
0167-4781

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Actinomycin D Binding to Unstructured, S
Actinomycin D Binding to Unstructured, Single-stranded DNA
✍ Hoon Yoo; Randolph L. Rill πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 100 KB πŸ‘ 1 views

## Abstract Actinomycin D is an anticancer antibiotic best know for inhibiting transcription by binding double‐stranded DNA. Tight, sequence selective binding of actinomycin to single‐stranded DNA is also known, however, and is implicated in biological activities including inhibition of (βˆ’) strand