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Binding of 1,25-dihydroxy-[3H]vitamin D3 in nuclear and cytosol fractions of whole mouse skin in vivo and in vitro

✍ Scribed by Thomas L. Clemens; Noboru Horiuchi; Minh Nguyen; Michael F. Holick

Book ID
115912359
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
347 KB
Volume
134
Category
Article
ISSN
0014-5793

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## Abstract 1Ξ±,25‐dihydroxy vitamin D~3~ (vitamin D~3~) has an important role during osteoblast differentiation as it directly modulates the expression of key bone‐related genes. Vitamin D~3~ binds to the vitamin D~3~ receptor (VDR), a member of the superfamily of nuclear receptors, which in turn i