1a,25-dihydroxy vitamin D3 has a major role in the regulation of the bone metabolism as it promotes the expression of key bone-related proteins in osteoblastic cells. In recent years it has become increasingly evident that in addition to its well-established genomic actions, 1a,25-dihydroxy vitamin
Plasma 1,25 Dihydroxy Vitamin D3Level and Expression of Vitamin D Receptor and Cathelicidin in Pulmonary Tuberculosis
β Scribed by P. Selvaraj; S. Prabhu Anand; M. Harishankar; K. Alagarasu
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 270 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0271-9142
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The plasma disappearance rate of 1,25-dihydroxyvitamin D3 [ 1,25-(OH)\*D3] was determined in rats after a single intravenous injection of the tritiated hormone. Tritiated 1,25-(OH)2D3 (120 Ci mmol-I) was administered to rats at a dose of 400 000 dpm kg-' body weight and the animals were bled between
## Abstract 1Ξ±,25βdihydroxy vitamin D~3~ (vitamin D~3~) has an important role during osteoblast differentiation as it directly modulates the expression of key boneβrelated genes. Vitamin D~3~ binds to the vitamin D~3~ receptor (VDR), a member of the superfamily of nuclear receptors, which in turn i
The present study investigates the presence of vitamin D receptor (VDR) in cells of the rat oligodendrocyte (OL) lineage. VDR transcripts were detected by in situ hybridization in a fraction of rat OL in secondary cultures. The VDR protein was shown to be co-localized in cells that are also recogniz