𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Binding and pharmacokinetic properties of novel 18F-labeled agents for in vivo imaging of tau pathology in Alzheimer's disease

✍ Scribed by Okamura, Nobuyuki; Furumoto, Shozo; Furukawa, Katsutoshi; Arai, Hiroyuki; Yanai, Kazuhiko; Kudo, Yukitsuka

Book ID
122400489
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
159 KB
Volume
6
Category
Article
ISSN
1552-5260

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A novel 18F-labeled pyridyl benzofuran d
A novel 18F-labeled pyridyl benzofuran derivative for imaging of Ξ²-amyloid plaques in Alzheimer’s brains
✍ Yan Cheng; Masahiro Ono; Hiroyuki Kimura; Shinya Kagawa; Ryuichi Nishii; Hideo S πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 456 KB

A potential probe for PET targeting b-amyloid plaques in Alzheimer's disease (AD) brain, FPYBF-1 (5-(5-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)-N,N-dimethylpyridin-2-amine), was synthesized and evaluated. In experiments in vitro, FPYBF-1 displayed high affinity for Ab(1-42) aggregates (K