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Binding and activation of C4 and C3 on the red cell surface by non-complement enzymes

✍ Scribed by Michael Kirschfink; Tibor Borsos

Book ID
118384158
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
807 KB
Volume
25
Category
Article
ISSN
0161-5890

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The effect of cadralazine and its active metabolite CGP 22639 on the covalent binding reaction of C4 and C3 has been studied. Trypsin-Sepharose was used to activate radio-labelled C3 and C4 and binding of the radio-labelled protein to the trypsin-Sepharose was measured. Cadralazine inhibited 50% of