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AUTOLYTIC FRAGMENTATION OF COMPLEMENT COMPONENTS C3 AND C4 AND ITS RELATIONSHIP TO COVALENT BINDING ACTIVITY

โœ Scribed by Robert B. Sim; Edith Sim


Book ID
118720425
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
1012 KB
Volume
421
Category
Article
ISSN
0890-6564

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Inhibition of complement components C3 a
โœ M. Andersson; A. Hanson; G. Englund; B. Dahlbรคck ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 537 KB

The effect of cadralazine and its active metabolite CGP 22639 on the covalent binding reaction of C4 and C3 has been studied. Trypsin-Sepharose was used to activate radio-labelled C3 and C4 and binding of the radio-labelled protein to the trypsin-Sepharose was measured. Cadralazine inhibited 50% of