Bile acids
β Scribed by Momir Mikov; J. Paul Fawcett
- Book ID
- 105731783
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 361 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0378-7966
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Bile acids are essential for the solubilization and transport of dietary lipids and are the major products of cholesterol metabolism. Results presented here show that bile acids are physiological ligands for the farnesoid X receptor (FXR), an orphan nuclear receptor. When bound to bile acids, FXR re
Major conjugated bile acids of human bile have been resolved by high-pressure liquid chromatography. The elutions are carried out in two stages on Corasil II or PPorasil columns; first, an alkaline solvent system (Zpropanokethyl acetate/ water/7 N ammonium hydroxide, 260:600:50:3) was used for separ