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Beta2-Adrenergic Receptor Gene Polymorphisms: Will the Important One Please Step Forward?

✍ Scribed by Martin C. Michel; Rainer Büscher


Book ID
119267734
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
63 KB
Volume
52
Category
Article
ISSN
1558-3597

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The beta-2-adrenergic receptor (beta(2-)-AR) has several single-nucleotide polymorphisms. These influence the functional response to adrenergic stimulation; genotypes homozygous for Gly16-Glu27 or Gly16-Gln27 alleles (Gly16-Glu/Gln27 haplotypes) are associated with enhanced response, whereas genotyp