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Effect of Polymorphisms in the Beta2-Adrenergic Receptor Gene (ADRB2) on Response to Long-Acting Beta2-Agonist (LABA) Therapy

✍ Scribed by Bleecker, E.R.; Postma, D.S.; Lawrance, R.; Meyers, D.A.; Ambrose, H.; Goldman, M.


Book ID
119279038
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
53 KB
Volume
119
Category
Article
ISSN
1097-6825

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Influence of beta-2 adrenergic receptor
✍ Juan Turnes; Manuel HernΓ‘ndez-Guerra; Juan G. Abraldes; Pau Bellot; Rafael Oliva πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 148 KB πŸ‘ 2 views

The beta-2-adrenergic receptor (beta(2-)-AR) has several single-nucleotide polymorphisms. These influence the functional response to adrenergic stimulation; genotypes homozygous for Gly16-Glu27 or Gly16-Gln27 alleles (Gly16-Glu/Gln27 haplotypes) are associated with enhanced response, whereas genotyp