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Polymorphisms of Beta2-Adrenergic Receptor Gene in Serbian Asthmatic Adults: Effects on Response to Beta-Agonists

✍ Scribed by Petrovic-Stanojevic, Natasa; Topic, Aleksandra; Nikolic, Aleksandra; Stankovic, Marija; Dopudja-Pantic, Vesna; Milenkovic, Branislava; Radojkovic, Dragica

Book ID
125816079
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
357 KB
Volume
18
Category
Article
ISSN
1177-1062

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The beta-2-adrenergic receptor (beta(2-)-AR) has several single-nucleotide polymorphisms. These influence the functional response to adrenergic stimulation; genotypes homozygous for Gly16-Glu27 or Gly16-Gln27 alleles (Gly16-Glu/Gln27 haplotypes) are associated with enhanced response, whereas genotyp