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Benzocyclobutenedione monoketal. A 1,4-dipole equivalent for anthracyclinone synthesis. Synthesis of (.+-.)-4-demethoxydaunomycinone

โœ Scribed by Jackson, Daniel K.; Narasimhan, Lakshmi; Swenton, John S.


Book ID
121223499
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
306 KB
Volume
101
Category
Article
ISSN
0002-7863

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Sumnary (\*)-7-Deoxy-4-demethoxydaunomyclnone((f) was cleanly resolved by forming a mixture of the dlastereomenc acetals((-)-2 and (+)-12 or (+)-zand (-)-19 with the title zm-dlol((+)-or (-)-g to give optically pure (R)(-)-A The method for racemizing the undesired enantiomer((S)(+)-2) was also explo