✦ LIBER ✦

Benzo[a]pyrene metabolism in mouse liver: Association of both 7,8-epoxidation and covalent binding of a metabolite of the 7,8-diol with the Ah locus

✍ Scribed by Jacques Van Cantfort; Jacques E. Gielen; Daniel W. Nebert

Book ID: 115778539
Publisher: Elsevier Science
Year: 1985
Tongue: English
Weight: 485 KB
Volume: 34
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(85)90655-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Metabolic Fate of Glutathione Conjugate

Metabolic Fate of Glutathione Conjugate of Benzo[a]pyrene-(7R,8S)-diol (9S,10R)-epoxide in Human Liver

✍ Sanjay K. Srivastava; Xun Hu; Hong Xia; Sanjay Awasthi; Shantu Amin; Shivendra V 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 97 KB

Glutathione conjugation of benzo[a]pyren

Glutathione conjugation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide in the perfused rat liver

✍ Bengt Jernström; Regina Brigelius; Helmut Sies 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 484 KB

Differences in mutagenicity of the optic

Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides

✍ A.W. Wood; R.L. Chang; W. Levin; H. Yagi; D.R. Thakker; DM. Jerina; A.H. Conney 📂 Article 📅 1977 🏛 Elsevier Science 🌐 English ⚖ 353 KB

A benzo[a]pyrene -7,8-dihydrodiol-9,10-e

A benzo[a]pyrene -7,8-dihydrodiol-9,10-epoxide is the major metabolite involved in the binding of benzo[a]pyrene to DNA in isolated viable rat hepatocytes

✍ Stephen W. Ashurst; Gerald M. Cohen 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 676 KB

Changes of mechanisms and product distri

Changes of mechanisms and product distributions in the hydrolysis of benzo[a]pyrene-7,8-diol 9,10,-epoxide metabolites induced by changes in pH

✍ Whalen, Dale L.; Montemarano, Jean A.; Thakker, Dhiren R.; Yagi, Haruhiko; Jerin 📂 Article 📅 1977 🏛 American Chemical Society 🌐 English ⚖ 378 KB

Synthesis of the phenolic esters of 1-hy

Synthesis of the phenolic esters of 1-hydroxy- and 3-hydroxy-7,8-diol-9,10-epoxides of benzo[a]pyrene

✍ Panna L. Kole; Subodh Kumar 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 291 KB

A chemical synthesis of the phenolic ester of the trio1 epoxide derivatives of carcinogenic benzo[alpyrene is described. The chemical synthesis of the various reactive metabolites has been an essential factor in elucidating the molecular mechanism that is responsible for QOlycyClic aromatic hydroca