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Synthesis of the phenolic esters of 1-hydroxy- and 3-hydroxy-7,8-diol-9,10-epoxides of benzo[a]pyrene

✍ Scribed by Panna L. Kole; Subodh Kumar

Publisher: Elsevier Science
Year: 1990
Tongue: French
Weight: 291 KB
Volume: 31
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)97450-1

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✦ Synopsis

A chemical synthesis of the phenolic ester of the trio1 epoxide derivatives of carcinogenic benzo[alpyrene is described.

The chemical synthesis of the various reactive metabolites has been an essential factor in elucidating the molecular mechanism that is responsible for QOlycyClic aromatic hydrocarbon

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