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Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of Tuberous Sclerosis Complex

✍ Scribed by Cambiaghi, Marco; Cursi, Marco; Magri, Laura; Castoldi, Valerio; Comi, Giancarlo; Minicucci, Fabio; Galli, Rossella; Leocani, Letizia

Book ID
122773416
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
630 KB
Volume
67
Category
Article
ISSN
0028-3908

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## Abstract Tuberous sclerosis complex (TSC) is a familial tumor syndrome characterized by the development of hamartomas in the brain, heart, kidney, and skin. Disease‐causing mutations in the __TSC1__ or __TSC2__ gene result in constitutive activation of the highly conserved mTOR signal transducti